Externally cued inphase bimanual training enhances preparatory premotor activity

► The measure of single-session training-related cortical activity modulation requires specific measurement tools depending upon training type (externally cued versus self-paced). ► Comparison of the cued MRP and self-paced BP reveal similar latencies, yet differing amplitudes and cortical localization. ► The preparatory periods of the visually-cued MRP and self-paced BP are generated by the lateral premotor cortex and SMA, respectively.