کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6009701 1579800 2017 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Case reportAdult-onset of mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS) syndrome with hypothyroidism and psychiatric disorders
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی سیستم های درون ریز و اتونومیک
پیش نمایش صفحه اول مقاله
Case reportAdult-onset of mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS) syndrome with hypothyroidism and psychiatric disorders
چکیده انگلیسی


- We presented an adult MELAS patient with a mutation at A3243G point.
- Hypothyroidism and psychiatric disorder were observed as accompanying symptoms.
- MRI findings were typical and provided clues to diagnose the underlying MELAS.

Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS) is a clinical syndrome associated with mitochondrial disorders (MIDs). This report illustrates a case of MELAS syndrome with hypothyroidism and psychiatric disorders, which is different from the common clinical manifestations of MELAS syndrome, such as exercise intolerance, migraine-like headaches, hearing loss and seizures etc. There are considerable interests in the possibility that mitochondrial dysfunction may play a role in the pathogenesis of endocrine dysfunctions and psychiatric disorders in MELAS syndrome.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: eNeurologicalSci - Volume 6, March 2017, Pages 16-20
نویسندگان
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