Prospective and “live” fast ripple detection and localization in the operating room: Impact on epilepsy surgery outcomes in children

In a prospective fashion, including “live” review, FR were detected in 80% of pediatric ECoG studies, and incomplete resection of FR cortex predicted postoperative seizures. These findings extend the notion that interictal FR are surrogate markers of the epileptogenic zone, and that their intraoperative localization could be used to inform prognosis and guide surgical resections in children.