کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6016171 | 1579926 | 2011 | 6 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Intrinsic epileptogenicity of gangliogliomas may be independent from co-occurring focal cortical dysplasia Intrinsic epileptogenicity of gangliogliomas may be independent from co-occurring focal cortical dysplasia](/preview/png/6016171.png)
SummaryGangliogliomas are a frequent cause of drug-resistant epilepsies in children. It remains unknown, however, whether gangliogliomas are intrinsically epileptogenic or if associated lesions contribute to their high epileptogenicity, i.e. associated focal cortical dysplasia (FCD). We report on a child operated twice for drug-resistant focal seizures symptomatic of a right temporal lobe lesion. Histological examination of the first, incomplete lesionectomy revealed tumor-associated FCD Type IIIb. The child was not seizure-free, and surface as well as intracerebral recordings were obtained during a second presurgical assessment. Histopathological examination of the second operation revealed a ganglioglioma. Intralesional EEG recordings from the ganglioglioma documented rhythmic bursts of fast activity suggesting that the high epileptogenicity of gangliogliomas is related to intrinsic epileptogenic activity.
Journal: Epilepsy Research - Volume 97, Issues 1â2, November 2011, Pages 208-213