کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6016192 | 1186103 | 2011 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Transition to seizure in photosensitive epilepsy
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
عصب شناسی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Transition to seizure in photosensitive epilepsy Transition to seizure in photosensitive epilepsy](/preview/png/6016192.png)
چکیده انگلیسی
Photosensitive epilepsy (PSE) offers a highly reproducible model to investigate whether changes in neuronal activity preceding the transition to an epileptic photoparoxysmal response (PPR) may be detected. We investigated this possibility in patients with idiopathic PSE using MEG, as well as normal controls and non-photosensitive epileptic patients of the same age group. Spectral analysis of the MEG signals recorded during intermittent light stimulation revealed relevant information in the phase spectrum. To quantify this effect, we introduced a second order response feature of the stimulus-triggered visual response preceding the PPR: the phase clustering index, which measures how close the phases of successive periods are grouped for each frequency component for all periods of the stimuli applied. We found that an enhancement of phase synchrony in the gamma-band (30-120Â Hz), harmonically related to the frequency of stimulation, preceded the stimulation trials that evolved into PPRs, and differed significantly from that encountered in trials not followed by PPR or in control subjects. Thus this index can be considered a valuable index of the pro-ictal transition to seizures in photosensitive epilepsy.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Epilepsy Research - Volume 97, Issue 3, December 2011, Pages 278-282
Journal: Epilepsy Research - Volume 97, Issue 3, December 2011, Pages 278-282
نویسندگان
Fernando H. Lopes da Silva, Graham F.A. Harding,