کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6041064 | 1189263 | 2016 | 25 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Relationship between muscle impairments, postural stability, and gait parameters assessed with lower-trunk accelerometry in myotonic dystrophy type 1
ترجمه فارسی عنوان
ارتباط بین اختلالات عضلانی، پایداری وضعیت و پارامترهای راه رفتن با استفاده از شتاب سنجی پایین تر در دیستروفی میوتونیک نوع 1
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
علوم اعصاب تکاملی
چکیده انگلیسی
This study evaluated gait using lower-trunk accelerometry and investigated relationships between gait abnormalities, postural instability, handgrip myotonia, and weakness in lower-limb and axial muscle groups commonly affected in myotonic dystrophy type 1 (DM1). Twenty-two patients (11 men, 11 women; ageâ=â42 years (range: 26-51)) with DM1 and twenty healthy controls (9 men, 11 women; ageâ=â44 years (range: 24-50)) participated in this study. Gait analysis using lower-trunk accelerometry was performed at self-selected walking pace. Postural stability was measured via center of pressure displacement analysis using a force platform during eyes-closed normal stance. Handgrip myotonia was quantified using force-relaxation curve modeling. Patients displayed lower walking speed, stride frequency, stride length, gait regularity, and gait symmetry. Strength of ankle plantar flexors, ankle dorsal flexors and neck flexors correlated with interstride regularity in the vertical direction (Ïâ=â0.57, Ïâ=â0.59, and Ïâ=â0.44, respectively; all Pâ<â0.05). Knee extension strength correlated with gait symmetry in the anteroposterior direction (Ïâ=â0.45, Pâ<â0.05). Center of pressure velocity was greater in patients and correlated with neck flexion and ankle plantar flexion weakness (Ïâ=ââ0.51 and Ïâ=ââ0.62, respectively; both Pâ<â0.05), and with interstride regularity in the vertical direction (Ïâ=ââ0.58, Pâ<â0.05). No correlation was found between handgrip myotonia and any other variable studied. Lower-trunk accelerometry allows the characterization of gait pattern abnormalities in patients with DM1. Further studies are required to determine the relevance of systematic gait analysis using lower-trunk accelerometry for patient follow-up and intervention planning.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neuromuscular Disorders - Volume 26, Issue 7, July 2016, Pages 428-435
Journal: Neuromuscular Disorders - Volume 26, Issue 7, July 2016, Pages 428-435
نویسندگان
Damien Bachasson, Amélie Moraux, Gwenn Ollivier, Valérie Decostre, Isabelle Ledoux, Teresa Gidaro, Laurent Servais, Anthony Behin, Tanya Stojkovic, Luc J. Hébert, Jack Puymirat, Bruno Eymard, Guillaume Bassez, Jean-Yves Hogrel,