کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6041426 1189289 2014 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The 2-min walk test is sufficient for evaluating walking abilities in sporadic inclusion body myositis
ترجمه فارسی عنوان
آزمون پیاده روی 2 دقیقه ای برای ارزیابی توانایی های پیاده روی در میوزیت جراحی پدیدار می شود
کلمات کلیدی
میوزیت ذاتی جسمی، اندازه گیری نتیجه، 2 دقیقه پیاده روی، 6 دقیقه پیاده روی، تابع،
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب تکاملی
چکیده انگلیسی
Sporadic inclusion body myositis causes progressive functional loss due to declining muscle strength. Although the underlying cause is unknown, clinical trials are underway to improve strength and function. Selection of appropriate outcome measures is critical for the success of these trials. The 6-min walk test has been the de facto standard for assessing function in neuromuscular disease; however, the optimal walking test has not been determined in this disease. In this study, 67 individuals with sporadic inclusion body myositis completed a battery of quantitative strength and functional tests including timed walking tests, patient-reported outcomes, and other tasks. The 2-min and 6-min walk tests are highly correlated to each other (r = 0.97, p < 0.001) and to all lower extremity strength, patient-reported, and functional measures in this population. All subjects completed the 2-min walk test, but 7% of subjects were unable to walk the full 6-min of the 6-min walk test due to fatigue. The 2-min walk test demonstrates similar correlation to all outcomes compared to the 6-min walk test, is less fatiguing and better tolerated. Results suggest that the 2-min walk test is a better alternative to tests of longer duration. Further research is needed to determine longitudinal changes on this outcome.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neuromuscular Disorders - Volume 24, Issue 3, March 2014, Pages 222-226
نویسندگان
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