کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6052479 | 1584180 | 2011 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Bisphosphonate-related osteonecrosis of the maxilla and sinusitis maxillaris
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
دندانپزشکی، جراحی دهان و پزشکی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Bisphosphonate-related osteonecrosis of the maxilla and sinusitis maxillaris Bisphosphonate-related osteonecrosis of the maxilla and sinusitis maxillaris](/preview/png/6052479.png)
چکیده انگلیسی
Bisphosphonates (BPs) are widely used as bone-stabilizers, but side effects of BP therapy include bisphosphonate-related osteonecrosis of the jaw (BRONJ), which is resistant to therapy. The aim of this study was to evaluate the outcome of maxillary BRONJ involving sinusitis maxillaris. 21 patients presenting with maxillary BRONJ, from 2005 to 2008, were included in the study. In 18 cases BP had been administered for carcinoma and in 3 cases for osteoporosis, with an average exposure time of 47.4 months. 12 patients spontaneously developed BRONJ. The 10 patients diagnosed with stage III BRONJ presented with concomitant sinusitis maxillaris. Despite treatment, there were six recurrences of BRONJ, four of them with additional sinusitis maxillaris. Whether BRONJ occurred spontaneously or after extraction there was no difference in the outcome. Patients with advanced maxillary BRONJ often suffer from sinusitis maxillaris, both of which are frequently resistant to therapy.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: International Journal of Oral and Maxillofacial Surgery - Volume 40, Issue 3, March 2011, Pages 285-291
Journal: International Journal of Oral and Maxillofacial Surgery - Volume 40, Issue 3, March 2011, Pages 285-291
نویسندگان
P. Maurer, T. Sandulescu, M.S. Kriwalsky, A. Rashad, S. Hollstein, I. Stricker, F. Hölzle, M. Kunkel,