کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6056214 1199139 2015 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Oral and maxillofacial pathologyMicroscopic analysis of molar-incisor malformation
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی دندانپزشکی، جراحی دهان و پزشکی
پیش نمایش صفحه اول مقاله
Oral and maxillofacial pathologyMicroscopic analysis of molar-incisor malformation
چکیده انگلیسی

ObjectiveMolar-incisor malformation (MIM) is a newly discovered type of dental anomaly that involves a characteristic root malformation of the permanent first molars. The aim of this study was to reveal the microstructure of MIM teeth in order to determine their origin.Study DesignFour MIM teeth were extracted from a 9-year-old girl due to severe mobility. The detailed microstructure of the teeth was determined by examinations with micro-computed tomography (micro-CT), hematoxylin and eosin (H&E) staining, immunohistochemical staining, and scanning electron microscopy to reveal the detailed microstructure.ResultsMicro-CT and H&E staining revealed the pulpal floor comprising three layers: upper, middle, and lower. Amorphous hard tissues and hyperactive cells were observed in the middle layer of the pulpal floor, and the cells stained positively for dentin sialoprotein and osteocalcin, but not for collagen XII.ConclusionThe results of the present study imply that MIM-affected molars probably result from inappropriate differentiation of the apical pulp and dental follicle.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology - Volume 119, Issue 5, May 2015, Pages 544-552
نویسندگان
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