کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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6058040 | 1199159 | 2012 | 9 صفحه PDF | دانلود رایگان |
ObjectiveThis study aimed to construct a preoperative predictive model of cervical lymph node metastasis using fluorine-18 fluorodeoxyglucose positron-emission tomography/computerized tomography (18F-FDG PET/CT) findings in patients with oral or oropharyngeal squamous cell carcinoma (SCC).Study DesignForty-nine such patients undergoing preoperative 18F-FDG PET/CT and neck dissection or lymph node biopsy were enrolled. Retrospective comparisons with spatial correlation between PET/CT and the anatomical sites based on histopathological examinations of surgical specimens were performed. We calculated a logistic regression model, including the SUVmax-related variable.ResultsWhen using the optimal cutoff point criterion of probabilities calculated from the model that included either clinical factors and delayed-phase SUVmax â¥0.087 or clinical factors and maximum standardized uptake (SUV) increasing rate (SUV-IR) ⥠0.100, it significantly increased the sensitivity, specificity, and accuracy (87.5%, 65.7%, and 75.2%, respectively).ConclusionsThe use of predictive models that include clinical factors and delayed-phase SUVmax and SUV-IR improve preoperative nodal diagnosis.
Journal: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology - Volume 113, Issue 2, February 2012, Pages 274-282