کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6058224 1199162 2014 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Oral and maxillofacial surgeryPrognostic factors in patients with head and neck squamous cell carcinoma with cN3 neck disease: a retrospective case-control study
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی دندانپزشکی، جراحی دهان و پزشکی
پیش نمایش صفحه اول مقاله
Oral and maxillofacial surgeryPrognostic factors in patients with head and neck squamous cell carcinoma with cN3 neck disease: a retrospective case-control study
چکیده انگلیسی

ObjectiveThis study examined prognostic factors in patients with head and neck squamous cell carcinoma with advanced neck disease.Study DesignThe records of 191 patients with previously untreated head and neck squamous cell carcinoma and metastatic cervical lymph node (LN) >6 cm (cN, n = 70) and 3.01 to 6 cm (control, n = 121) in the greatest dimension were reviewed. Univariate and multivariate analyses were used to identify factors associated with disease-free survival (DFS) and locoregional control (LRC).ResultsIn the cN3 group, independent variables for DFS were age, active drinking, LN size, and extranodal extension (P < .05), and that for LRC was age (P = .025). In the control group, independent variables for DFS were tumor location and differentiation and LN bilaterality (P < .05), and that for LRC was LN bilaterality (P = .011).ConclusionsThe survival of cN3 patients is affected by host and nodal characteristics including age, drinking, nodal size, and extranodal extension.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology - Volume 117, Issue 2, February 2014, Pages 178-185
نویسندگان
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