Nanocomplexation-assisted solubilization of pDNA in organic solvents for improved microencapsulation

► pDNA can be solubilized in organic solvent by nanocomplexation using PEG-b-PLL. ► Nanocomplexes formed by PEG-b-PLL/pDNA in organic solvent exhibit spherical shape. ► pDNA can be efficiently microencapsulated by solubilizing in organic solvent.