کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
607856 | 1454605 | 2013 | 8 صفحه PDF | دانلود رایگان |
Supported lipid bilayers (SLBs) were prepared on glass and silicon slides grafted with polyethylene glycol (PEG) and covalently bound cholesteryl anchors to fix the lipid bilayer on the surface. Phospholipid bilayers and bilayers modified by addition of covalently bound PEG were investigated. Using contact angle measurements, the surface energy components of bilayer surfaces were analyzed using van Oss’ and Owens–Wendt’s methods. A quantitative correlation between the polar proton acceptor component of the surface energies and the respective hydration densities was proven for SLBs of pure lipids. We could show that the presence of PEG in the SLB produces a significant change of the proton acceptor component. Regarding the correlation between the surface energies and the hydration densities of SLBs with PEG, we were able to show a dependency on the PEG conformation.
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► First proof of air stable supported lipid bilayers (SLBs) with polyethylene glycol.
► Analysis of the surface energy components of SLBs with different methods.
► Proof of correlation between proton acceptor component γ− and hydration densities.
► Inclusion of PEG into the SLB changes γ− significantly.
► Hydration densities and γ− of SLBs with PEG depend on the PEG conformation.
Journal: Journal of Colloid and Interface Science - Volume 390, Issue 1, 15 January 2013, Pages 267–274