کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6084886 1589116 2016 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Selected Topics: ToxicologySynthetic Cannabinoids and Their Effects on the Cardiovascular System
ترجمه فارسی عنوان
موضوعات انتخاب شده: سم شناسی کانابینوئید سنتتیک و اثرات آن بر سیستم قلبی عروقی
کلمات کلیدی
کانابینوئید مصنوعی، سیستم قلبی عروقی، سم شناسی،
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی طب اورژانس
چکیده انگلیسی

BackgroundIn the past couple of years, there has been an outbreak of synthetic cannabinoid (SC) use in major cities in the United States. Patients can present with various symptoms affecting the central nervous and cardiovascular systems. The effects of endocannabinoid on contractility and Ca2+ signaling have been shown through both cannabinoid receptors and a direct effect on ion channels. These effects result in abnormalities in ionotropy, chronotropy, and conduction.Case ReportHere we report on two cases of SC abuse and abnormalities in the cardiovascular system. These cases raise concerns about the adverse effects of SCs and the possibility of QTc prolongation and subsequent complications when using antipsychotic medication in the presence of SC abuse.Why Should an Emergency Physician be Aware of This?Given the rise in SC use and the potential effect on the cardiovascular system, physicians need to be mindful of potential cardiac complications, such as QTc prolongation and torsade de pointe, especially when administering medications that have the potential to cause QTc prolongation.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: The Journal of Emergency Medicine - Volume 50, Issue 2, February 2016, Pages 258-262
نویسندگان
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