کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6085192 1589119 2015 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Pharmacology in Emergency MedicineTrends and Characteristics of Emergency Department Patients Prescribed Novel Oral Anticoagulants
ترجمه فارسی عنوان
فارماکولوژی در پزشکی اضطراری. رشته ها و ویژگی های بیماران گروه اورژانس. ریشه های ضد انعقادی خوراکی.
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی طب اورژانس
چکیده انگلیسی

BackgroundSince 2010, several novel oral anticoagulants (NOACs) have been approved by the United States Food and Drug Administration for the use in the prevention of cerebrovascular accidents (CVAs) in nonvalvular atrial fibrillation.ObjectiveOur aim was to describe the trends and characteristics of NOAC-related emergency department (ED) visits.MethodsRetrospective review of data from an ED tracking system of all visits that had a medication reconciliation with an NOAC or warfarin to a tertiary care ED between October 2010 and August 2014. Basic demographics, admission rate, admission diagnoses, and trends were analyzed.ResultsThe rate of warfarin visits was stable at 50-60 patients per month (PPM) per 1000 ED visits, however, the rate of dabigatran visits rose to 3-5 PPM/1000 until 2012 and has stayed stable, while rivaroxaban and apixaban have been gradually increasing to 2-4 and 1-2 PPM/1000, respectively. The admission rate for warfarin was 63.7% and for NOACs was 58.1%, compared to baseline admission rate of 35.5%. The hemorrhagic diagnosis rate was similar for warfarin and the NOACs (8.8% and 8.0%, respectively). There were three significantly different admission diagnoses: there were more admission for atrial fibrillation (5.4% vs. 1.9%) and CVA/transient ischemic attack (5.3% vs. 3.0%) in the NOAC group, while there were more admissions for intracranial hemorrhage (2.7% vs. 0.8%) in the warfarin group.ConclusionsThere has been a steady increase of ED patients who are taking an NOAC. There is a nearly double admission rate for an anticoagulated patient regardless of reason for ED visit. There appears to be no difference between rates of bleeding between warfarin and NOACs, although patients taking NOACs are admitted less often for intracranial hemorrhage.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: The Journal of Emergency Medicine - Volume 49, Issue 5, November 2015, Pages 693-697
نویسندگان
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