کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6088614 1207712 2014 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Liver, Pancreas and Biliary TractDiurnal changes of critical flicker frequency in patients with liver cirrhosis and their relationship with sleep disturbances
ترجمه فارسی عنوان
کبد، پانکراس و ترشحات صفراوی تغییرات روزانه فریتوری بحرانی در بیماران مبتلا به سیروز کبدی و ارتباط آنها با اختلالات خواب
کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی غدد درون ریز، دیابت و متابولیسم
چکیده انگلیسی

BackgroundWe aimed to measure the diurnal changes of critical flicker frequency in healthy subjects and cirrhotic patients and to investigate their relationship with sleep disturbance.MethodsCirrhotic patients and healthy volunteers were included. All groups completed the Pittsburgh Sleep Quality Index and a simple sleep questionnaire. Sleep disturbance was defined as a Pittsburgh Sleep Quality Index score of >5. Critical flicker frequency was measured twice a day to detect diurnal abnormalities.ResultsOverall, 59 cirrhotic patients (54.2% males, Mean Age 59 ± 11 years) and 18 controls (39.9% males, Mean Age 58 ± 9 years) were included. Sleep disturbances were more common in cirrhotics (66.1%) than controls (38.9%, p < 0.05). In cirrhotics, the critical flicker frequency was not related to decompensation. The nocturnal values were higher than the morning values in cirrhotics (64.4%), but not in controls (p < 0.0001). Additionally, sleep disturbances were more common in cirrhotics who had higher nocturnal values (p < 0.05).ConclusionsChanges in the diurnal critical flicker frequency were observed in cirrhotics but not in controls. Sleep disturbances in cirrhotics appear to be associated with deviations of the diurnal rhythm of critical flicker frequency rather than with clinical parameters such as the clinical stages of cirrhosis and the Model For End-Stage Liver Disease and Child-Pugh scores.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Digestive and Liver Disease - Volume 46, Issue 12, December 2014, Pages 1111-1115
نویسندگان
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