کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6088785 1207731 2014 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Review ArticleSmall bowel adenocarcinoma: Epidemiology, risk factors, diagnosis and treatment
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی غدد درون ریز، دیابت و متابولیسم
پیش نمایش صفحه اول مقاله
Review ArticleSmall bowel adenocarcinoma: Epidemiology, risk factors, diagnosis and treatment
چکیده انگلیسی

Small bowel adenocarcinomas are rare tumours, but their incidence is increasing. Their most common primary location is the duodenum. The few studies that have collected data regarding small bowel adenocarcinoma are not homogeneous and are widely spread over time. Even though these tumours are most often sporadic, some predisposing diseases have been identified, among which Crohn's disease and genetic syndromes. Early diagnosis of small bowel adenocarcinoma remains difficult despite significant radiological and endoscopic progress. After surgical resection the main prognostic factor is node invasion; in this case, adjuvant chemotherapy can be expected to be beneficial, although this has not been established by randomised trials. For metastatic disease, platinum-based chemotherapy seems to be the most effective treatment. Targeted therapies have not yet been evaluated in this type of cancer.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Digestive and Liver Disease - Volume 46, Issue 2, February 2014, Pages 97-104
نویسندگان
, , , , , , , ,