کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6088795 1207731 2014 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Digestive EndoscopyEndoscopic resection for superficial colorectal neoplasia in Italy: A prospective multicentre study
ترجمه فارسی عنوان
آندوسکوپی گوارشی برداشتن اندوسکوپی برای نئوپلاسیک سطحی در ایتالیا: یک مطالعه چند بعدی مرکزیت
کلمات کلیدی
عوارض جانبی، نئوپلاسی کولورکتال، برداشتن آندوسکوپی، موکوسکتومی، عواقب،
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی غدد درون ریز، دیابت و متابولیسم
چکیده انگلیسی

BackgroundSince there are few prospective studies on colorectal endoscopic resection to date, we aimed to prospectively assess safety and efficacy of endoscopic resection in a cohort of Italian patients.MethodsProspective multicentre assessment of resection of sessile polyps or non-polypoid lesions ≥ 10 mm in size or smaller (if depressed). Outcome measures included complete excision, morbidity, mortality, and residual/recurrence at 12 months.ResultsOverall, 1012 resections in 928 patients were analysed (62.4% sessile polyps, 28.8% laterally spreading tumours, 8.7% depressed non-polypoid lesions). Lesions were prevalent in the proximal colon. Enbloc resection was possible in 715/1012 cases (70.7%), whereas piecemeal resection was required in 297 (29.3%). Endoscopically complete excision was achieved in 866 cases (85.6%). Adverse events occurred in 83 (8.2%), and no deaths occurred. Independent predictors of 12-month residual/recurrence were the location of the lesion in the proximal colon (OR 2.22 [95% CI 1.16-4.26]; p = 0.015) and piecemeal endoscopic resection (OR 2.76 [95% CI 1.56-4.87]; p = 0.0005). Limitations of the study were: potential expertise bias, no data on eligible and potentially resectable excluded lesions, high percentage of lesions < 20 mm, follow-up limited to 1 year.ConclusionIn this registry study the endoscopic resection of colorectal lesions was safe and achieved high rates of long-term endoscopic clearance.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Digestive and Liver Disease - Volume 46, Issue 2, February 2014, Pages 146-151
نویسندگان
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