کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6088833 1207747 2013 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Digestive EndoscopyLong-term outcome of early gastric cancer after endoscopic submucosal dissection: Expanded indication is comparable to absolute indication
ترجمه فارسی عنوان
آندوسکوپی گوارشی نتایج طولانی مدت سرطان اولیه در معرض انسداد زیر انقباض اندوسکوپیک: نشانگر گسترده با نشانگر مطلق قابل مقایسه است
کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی غدد درون ریز، دیابت و متابولیسم
چکیده انگلیسی

BackgroundEndoscopic submucosal dissection has become widely used for early gastric cancer with an expanded indication, although there is no strong consensus. We aimed to compare the clinical and long-term oncological outcome after endoscopic submucosal dissection according to indication.MethodsRetrospective review of 1152 patients with 1175 lesions who had undergone endoscopic submucosal dissection for early gastric cancer at tertiary educational hospital in Korea, between March 2005 and November 2011. Of these, 366 and 565 lesions were included in the absolute and expanded indication groups, respectively.ResultsEn bloc resection rates were not significantly different between the absolute and expanded indication groups. The complete resection rate was higher in the absolute indication group versus the expanded indication group (94.8% vs. 89.9%, respectively; P = 0.008). In the expanded indication group, complete resection rate was higher in the differentiated versus undifferentiated tumour subgroups (92.9% vs. 78.4%, respectively; P < 0.001). Recurrence rates were 7.7% in the absolute indication group vs. 9.3% in the expanded indication group (P = 0.524). Disease-free survival was not significantly different between the two indication groups (P = 0.634).ConclusionsEndoscopic submucosal dissection for early gastric cancer with expanded indication is a feasible approach to disease management. Periodic endoscopic follow-up is necessary to detect cancer recurrence.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Digestive and Liver Disease - Volume 45, Issue 8, August 2013, Pages 651-656
نویسندگان
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