Self-assembly of β-cyclodextrin and pluronic into hollow nanospheres in aqueous solution

► β-CD and PEG-PPG-PEG could form hollow spheres due to the formation of coil-rod inclusion complexes. ► In these inclusion complexes, β-CDs are stacked along PPG to form rod block and PEG act as coil block. ► The β-CD/PEG-PPG-PEG complexes show dependence of β-CDs concentration and temperature.