کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6091743 1209281 2015 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Original articleA meta-analysis of single-stage versus two-stage management for concomitant gallstones and common bile duct stones
ترجمه فارسی عنوان
مقاله مقدماتی فرآیند تجزیه و تحلیل تک مرحله ای در مقابله با دو مرحله مدیریت برای سنگ های صفراوی همراه و سنگ های کانال مجرای صفراوی
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی بیماری‌های گوارشی
چکیده انگلیسی

SummaryObjectiveTo conduct a randomized controlled trial (RCT) meta-analysis to evaluate the safety and effectiveness of single-stage [laparoscopic cholecystectomy (LC) + laparoscopic common bile duct exploration (LCBDE)] vs. two-stage management [preoperative endoscopic retrograde cholangiopancreatography (ERCP) + LC] for concomitant gallstones and common bile duct stones.MethodsRCTs that met the inclusion criteria for data extraction were identified from electronic databases (PubMed, Embase, Science Citation Index, and the Cochrane Library) up to August 2014. The relevant congressional proceedings were also searched. The primary outcomes were stone clearance from the common bile duct, postoperative morbidity and mortality. The secondary outcomes were conversion to other procedures, length of hospital stay, total operative time, and hospitalization charges. The outcomes were calculated as odds ratios (ORs) with 95% confidence intervals (CIs) using RevMan 5.2.ResultsEight RCTs, which included 1130 patients, were identified for analysis in our study. The meta-analysis revealed that the common bile duct stone clearance rate in the single-stage group was higher (OR = 1.56, 95% CI: 1.05 to 2.33, P = 0.03). The lengths of hospital stay (MD = −1.02, 95% CI: −1.99 to −0.04, P = 0.04) and total operative times (MD = −16.78, 95% CI: −27.55 to −6.01, P = 0.002) were also shorter in the single-stage group. There was no statistically significant difference between the two groups regarding postoperative morbidity (OR = 1.12, 95% CI: 0.79 to 1.59, P = 0.52), mortality (OR = 0.29, 95% CI: 0.06 to 1.41, P = 0.13) and conversion to other procedures (OR = 0.82, 95% CI: 0.37 to 1.82, P = 0.62).ConclusionSingle- and two-stage management for cholecysto-choledocholithiasis had similar mortality and complication rates; however, the single-stage strategy was better in terms of stone clearance, hospital stay and total operative time.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Clinics and Research in Hepatology and Gastroenterology - Volume 39, Issue 5, October 2015, Pages 584-593
نویسندگان
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