کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6100472 | 1211070 | 2011 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Successful treatment with adalimumab in a familial case of gastrointestinal Behcet's disease
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موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
بیماریهای گوارشی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Successful treatment with adalimumab in a familial case of gastrointestinal Behcet's disease Successful treatment with adalimumab in a familial case of gastrointestinal Behcet's disease](/preview/png/6100472.png)
چکیده انگلیسی
We present here two siblings with a history of recurrent oral and genital ulcers, neurological and gastrointestinal manifestations. The diagnosis of Behçet's disease in a context of familial aggregation was assumed. Facing repeated steroid-dependent flares and failure of maintenance therapies with colchicine and intolerance to pentoxifilline and disulone, adalimumab was started. Rapid response was observed in both patients, with clinical remission after induction therapy, which currently sustains under maintenance schedule. This case report suggests the effectiveness of adalimumab as first anti-TNFα in case of steroid-dependent/resistant gastrointestinal BD.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Crohn's and Colitis - Volume 5, Issue 4, August 2011, Pages 364-368
Journal: Journal of Crohn's and Colitis - Volume 5, Issue 4, August 2011, Pages 364-368
نویسندگان
Chiara De Cassan, Bénédicte De Vroey, Catherine Dussault, Eric Hachulla, Sebastien Buche, Jean-Frédéric Colombel,