کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
610226 880643 2010 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Anion effects on anti-microbial activity of poly[1-vinyl-3-(2-sulfoethyl imidazolium betaine)]
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی شیمی کلوئیدی و سطحی
پیش نمایش صفحه اول مقاله
Anion effects on anti-microbial activity of poly[1-vinyl-3-(2-sulfoethyl imidazolium betaine)]
چکیده انگلیسی

Recent investigations in the anti-microbial properties of the functional polymers are predominantly focused on the structure of the cationic moieties. In the present study, we investigated that the nature of the anion present in polysulfobetaines affects activity against certain microorganisms and their anti-microbial properties have been rationalized in terms of the structure–activity relationship. Vinyl imidazolium-based polysulfobetaines were prepared by the quaternization of poly(N-vinyl imidazole) with sodium salt of 2-bromo ethanesulfonic acid. The bromide counter anion of the resulting polymer was exchanged with different anions to generate a series of polymers. These were characterized by FTIR, DSC, XRD, SEM, elemental analysis (C, H, N and S) and viscosity measurements. The anti-microbial activity studies were carried against three fungi (Aspergillus niger, Byssochlamys fulva and Mucor circenelliods) and two bacteria (Bacillus coagulans BTS-3 and Pseudomonas aeruginosa BTS-2). The nature of the anion affects the structure of polysulfobetaine by realignment of polymer chains. The anion-dependent anti-microbial properties of polysulfobetaines result from the interaction of the microbes at the polymer interface.

A series of polysulfobetaines was prepared by anion exchange reactions. Polysulfobetaines exhibited strong anion-dependent antifungal as well as anti-bacterial properties, and are good candidates for biomedical applications.Figure optionsDownload high-quality image (94 K)Download as PowerPoint slide

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Colloid and Interface Science - Volume 344, Issue 1, 1 April 2010, Pages 90–96
نویسندگان
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