کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6145787 1594915 2014 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Sex-specific effects of maternal anthropometrics on body composition at birth
ترجمه فارسی عنوان
اثرات متفاوتی از آنتروپومتری مادر در ترکیب بدن در هنگام تولد
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی پزشکی و دندانپزشکی (عمومی)
چکیده انگلیسی

ObjectiveThe purpose of this study was to assess whether maternal factors that are associated with fetal lean and fat mass differ between sexes.Study DesignSecondary analysis of a prospective cohort that delivered by scheduled cesarean section from 2004-2013. Maternal blood was collected before surgery for metabolic parameters. Placental weight and neonatal anthropometrics were measured within 48 hours. Anthropometric differences between sexes were assessed with the Student t test. Multiple stepwise regression analysis assessed the relationship between independent maternal variables and neonatal lean body mass (LBM), fat mass (FM), or percentage of fat as dependent variables in male and female infants combined and separately.ResultsWe analyzed 360 women with normal glucose tolerance and a wide range of pregravid body mass index (16-64 kg/m2) and their offspring (male, 194; female, 166). Male infants had more FM (mean difference, 40 ± 18 g; P = .03) and LBM (mean difference, 158 ± 34 g; P < .0001) than female infants. Percentage of body fat and measured maternal variables did not differ between sexes. In both sexes, placental weight had the strongest correlation with both neonatal LBM and FM, which accounted for 20-39% of the variance. In male infants, maternal height, body mass index, and weight gain were significant predictors of both lean and fat mass. In female infants, plasma interleukin-6 and C-reactive protein, respectively, were associated independently with percentage of body fat and LBM.ConclusionOur findings suggest that the body composition and inflammatory environment of the mother modulate the metabolic fitness of neonates, as predicted by fat and lean mass, in a sex-specific manner.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: American Journal of Obstetrics and Gynecology - Volume 211, Issue 3, September 2014, Pages 292.e1-292.e9
نویسندگان
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