کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6146771 | 1594950 | 2012 | 8 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Labor induction in term premature rupture of membranes: comparison between oxytocin and dinoprostone followed 6 hours later by oxytocin Labor induction in term premature rupture of membranes: comparison between oxytocin and dinoprostone followed 6 hours later by oxytocin](/preview/png/6146771.png)
ObjectiveThe aim of this randomized study was to compare 2 protocols for inducing labor in women with premature rupture of membranes (PROM) at term.Study DesignWomen with PROM and a Bishop score â¤5 were randomly assigned to receive either an intravenous oxytocin infusion (n = 223) or a dinoprostone pessary followed 6 hours later by an intravenous oxytocin infusion (n = 227).ResultsVaginal delivery within 24 hours of labor induction increased significantly with sustained-released dinoprostone followed by oxytocin infusion (78.5% vs 63.3%; relative risk, 1.23; 95% confidence interval, 1.09-1.39; P = .001). Maternal and neonatal outcomes were similar between the groups.ConclusionSustained-released dinoprostone followed 6 hours later by an oxytocin infusion in term women with PROM was associated with a higher rate of vaginal delivery within 24 hours, and no difference in maternal-neonatal complications was observed compared with oxytocin infusion alone.
Journal: American Journal of Obstetrics and Gynecology - Volume 206, Issue 1, January 2012, Pages 60.e1-60.e8