کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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6146782 | 1594950 | 2012 | 7 صفحه PDF | دانلود رایگان |
ObjectiveWe sought to investigate seasonal variation in fetal growth, accounting for important sociodemographic, biological, and environmental exposures.Study DesignRecords of births 1998 through 2006 in Perth, Western Australia were obtained (N = 147,357). We investigated small for gestational age and sex and the proportion of optimal birthweight (POBW) in relation to seasonal exposures (season, temperature, sunlight) by trimester of pregnancy. Adjustment was made for a wide range of risk factors.ResultsThe POBW for neonates with third trimesters predominantly in summer was 0.18% (0.00-0.36%) lower than for those in winter. POBW decreased by 0.14% (0.01-0.27%) per interquartile range increase in third-trimester temperature (9.15°C). An interquartile range increase in temperature over pregnancy (0.73°C) was associated with an odds ratio of 1.02 (95% confidence interval, 1.00-1.05) for small for gestational age and sex.ConclusionReduced fetal growth was associated with elevated ambient temperatures throughout and late in pregnancy, independently of air pollution and other risk factors.
Journal: American Journal of Obstetrics and Gynecology - Volume 206, Issue 1, January 2012, Pages 74.e1-74.e7