کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6150720 1596429 2016 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Evaluating the treatment of obstructive sleep apnea comorbid with insomnia disorder using an incomplete factorial design
ترجمه فارسی عنوان
ارزیابی درمان آپنه انسدادی خواب همراه با اختلال بی خوابی با استفاده از یک طرح فاکتوریل ناقص
کلمات کلیدی
آپنه انسدادی خواب اختلال بی خوابی، کارآزمایی بالینی تصادفی طراحی فاکتوریل ناقص
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی پزشکی و دندانپزشکی (عمومی)
چکیده انگلیسی

Chronic insomnia disorder is a prevalent condition and a significant proportion of these individuals also have obstructive sleep apnea (OSA). These two sleep disorders have distinct pathophysiology and are managed with different treatment approaches. High comorbidity rates have been a catalyst for emerging studies examining multidisciplinary treatment for OSA comorbid with insomnia disorder. In this article, we describe a randomized clinical trial of cognitive behavioral treatment for insomnia (CBT-I) and positive airway pressure (PAP) for OSA. Participants are randomized to receive one of three treatment combinations. Individuals randomized to treatment Arm A receive sequential treatment beginning with CBT-I followed by PAP, in treatment Arm B CBT-I and PAP are administered concurrently. These treatment arms are compared to a control condition, treatment Arm C, where individuals receive PAP alone. Adopting an incomplete factorial study design will allow us to evaluate the efficacy of multidisciplinary treatment (Arms A & B) versus standard treatment alone (Arm C). In addition, the random allocation of individuals to the two different combined treatment sequences (Arm A and Arm B) will allow us to understand the benefits of the sequential administration of CBT-I and PAP relative to concurrent treatment of PAP and CBT-I. These findings will provide evidence of the clinical benefits of treating insomnia disorder in the context of OSA.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Contemporary Clinical Trials - Volume 47, March 2016, Pages 146-152
نویسندگان
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