Platinum-encapsulated zeolitically microcapsular catalyst for one-pot dynamic kinetic resolution of phenylethylamine

The platinum-encapsulated zeolitically microcapsular catalyst, associated with the immobilized Candida antartica lipase B (Novozyme®435), is successfully employed in the dynamic kinetic resolution of phenylethylamine. A conversion of 80% and a selectivity of 95% are achieved, and negligible loss of activity is detected even after reaction of 5 runs. It is found that the existence of the silicalite-1 shell not only effectively prevents the deactivation of both enzyme and Pt by isolating them in different regions of reaction system, but also significantly reduces the formation of by-products on the Pt nanoparticles within the protected space of zeolitic microcapsule. Such features of zeolitic shell should further promote the designing of various catalysts for multistep reaction network.

Platinum-encapsulated zeolitic microcapsules are successfully employed in dynamic kinetic resolution of phenylethylamine with high activity and selectivity due to promising protective effect of the zeolitically microcapsular structure.Figure optionsDownload high-quality image (109 K)Download as PowerPoint slideHighlights
► Platinum-encapsulated ZMCs are successfully employed in DKR of phenylethylamine.
► ZMC structure of catalyst promises its activity, selectivity and reusability.
► Isolation effect of zeolitic shell prohibits the deactivation of Pt and enzyme.
► The protected space within ZMC limits the formation of by-product.