RETRACTED: Kidney Function and Rate of Bone Loss at the Hip and Spine: The Canadian Multicentre Osteoporosis Study

This article has been retracted: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy).This article has been retracted at the request of coauthors Victoria J.D. Swan, Jacques P. Brown, David A. Hanley, Jerilynn C. Prior, Alexandra Papaioannou, Lisa Langsetmo, and Robert G. Josse, on behalf of the Canadian Multicentre Osteoporosis Study Research Group.Following the finding of “data falsification and/or fabrication” by the first author, Dr Sophie A. Jamal, in an article published in JAMA,1 thereafter retracted,2 the Canadian Multicentre Osteoporosis Study Group (CaMos) conducted an investigation of the CaMos manuscripts for which Dr Jamal was the first or responsible author. Dr Jamal, formerly the Co-Director of the Toronto CaMos Centre, was responsible for the integrity of the data and the accuracy of the data analysis in this article. Dr David Goltzman, Principal Investigator of CaMos, informed AJKD that the CaMos investigation found inconsistencies in this article that are difficult to reconcile with the CaMos source data; moreover, the investigation determined that the results of the reanalysis do not support the conclusions as originally published. Dr Jamal, who was both first and corresponding author, has declined to provide any comments or further information. Based on the CaMos investigation, Dr Goltzman, on behalf of co-authors Swan, Brown, Hanley, Prior, Papaioannou, Langsetmo, and Josse, contacted AJKD to ask that this article be retracted. Drs Goltzman, Swan, Brown, Hanley, Prior, Papaioannou, Langsetmo, and Josse recognize the seriousness of this issue; apologize unreservedly to the editors, reviewers, and readers of AJKD; and are committed to the integrity of the biomedical literature and believe there is no risk that these possibly invalid conclusions harmed CaMos participants or patients with osteoporosis.References1. Jamal SA, Hamilton CJ, Eastell R, Cummings SR. Effect of nitroglycerin ointment on bone density and strength in postmenopausal women: a randomized trial. JAMA. 2011;305(8):800-807.2. Eastell R, Hamilton CJ, Cummings SR. Notice of retraction: Jamal SA, et al. Effect of nitroglycerin ointment on bone density and strength in postmenopausal women: a randomized trial. JAMA. 2011;305(8):800-807. JAMA. 2016;315(4):418-419.