کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6166337 | 1250299 | 2015 | 7 صفحه PDF | دانلود رایگان |
ObjectiveTo characterize changes in indices of urinary function in prostatectomy patients with presurgical voiding symptoms.MethodsA retrospective analysis of our prostate cancer database identified robot-assisted radical prostatectomy patients between April 2007 and December 2011 who completed pre- and postsurgical (24Â months) Expanded Prostate Cancer Index Composite-26 surveys. Gleason score, margins, D'Amico risk, prostate-specific antigen, radiotherapy, and nerve-sparing status were tabulated. Survey questions addressed urinary irritation/obstruction, incontinence, and overall bother. Responses were averaged to calculate a urinary sum (US) score. Patients were stratified according to the severity of their baseline urinary bother (UB), and changes in urinary indices determined at 24Â months.ResultsA total of 737 patients were included. Postsurgical improvement in urinary obstruction, bother, and sum score was related to baseline UB (PÂ <.001). Men with severe baseline bother had the greatest improvement in US (+9.3), whereas those with asymptomatic baseline UB experienced a decline in US (â2.8). All patients experienced a decline in urinary incontinence of 6.3-8.3 that was independent of baseline bother (PÂ = .507). Patients with severe UB experienced positive outcomes, whereas those at asymptomatic baseline experienced negative US outcomes. Negative urinary incontinence outcomes were unrelated to baseline UB. Age, radiotherapy, and nerve-sparing status were not associated with improved UB (PÂ = .029). However, baseline UB was significantly associated with improvement in postsurgical UB (PÂ = .001).ConclusionBaseline UB is a predictor of postsurgical improvement in urinary function. These data are helpful when counseling a subset of robot-assisted laparoscopic radical prostatectomy patients with severe preoperative urinary symptoms.
Journal: Urology - Volume 86, Issue 4, October 2015, Pages 817-823