Rising Incidence of Acute Prostatitis Following Prostate Biopsy: Fluoroquinolone Resistance and Exposure Is a Significant Risk Factor

Prior fluoroquinolone intake is a significant risk factor behind a rising incidence of acute prostatitis after transrectal prostate biopsy. Identified pathogens are mostly Gram-negative organisms with a high rate of fluoroquinolone resistance. Alternative prophylaxis regimens for the biopsy procedure should be considered in patients with recent quinolone intake.