Formal analysis of the surgical pathway and development of a new software tool to assist surgeons in the decision making in primary breast surgery

- Decision making in oncological surgery of the breast can be a complex choice nowadays.
- Patients should be at the center of the decision process.
- An automatic tool can be useful in supporting proper decisions.
- The final choice should aim at cosmetic results and surgical safety.
- Clinical Decision Support Systems (CDSS) emphasizes flexibility and adaptability to accommodate changes in the scenario.

BackgroundThe increased complexity of the decisional process in breast cancer surgery is well documented. With this study we aimed to create a software tool able to assist patients and surgeons in taking proper decisions.MethodologyWe hypothesized that the endpoints of breast cancer surgery could be addressed combining a set of decisional drivers. We created a decision support system software tool (DSS) and an interactive decision tree. A formal analysis estimated the information gain derived from each feature in the process. We tested the DSS on 52 patients and we analyzed the concordance of decisions obtained by different users and between the DSS suggestions and the actual surgery. We also tested the ability of the system to prevent post breast conservation deformities.ResultsThe information gain revealed that patients preferences are the root of our decision tree. An observed concordance respectively of 0.98 and 0.88 was reported when the DSS was used twice by an expert operator or by a newly trained operator vs. an expert one. The observed concordance between the DSS suggestion and the actual decision was 0.69. A significantly higher incidence of post breast conservation defects was reported among patients who did not follow the DSS decision (Type III of Fitoussi, N = 4; 33.3%, p = 0.004).ConclusionThe DSS decisions can be reproduced by operators with different experience. The concordance between suggestions and actual decision is quite low, however the DSS is able to prevent post- breast conservation deformities.