کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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6172912 | 1599780 | 2016 | 5 صفحه PDF | دانلود رایگان |
ObjectiveTo evaluate the result of laparoscopic endometrioma excision in fertility outcome of advanced endometriosis patients.Study designThe study was designated as historical cohort, in a private referral center of advance laparoscopy. 111 infertile patients, diagnosed as endometriosis, were divided in two groups: DIE (deep infiltrative endometriosis) and endometrioma (case group), and patients with only DIE (without endometrioma ((control group). All patients underwent global laparoscopic resection of DIE lesion (both groups) and laparoscopic excisional cystectomy of endometrioma (case groups). Patients were followed for fertility outcomes and data were analyzed by Kaplan-Meier test and COX regression using SPSS software.ResultsAfter adjusting covariates, the Kaplan-Meier analysis of cumulative pregnancy rates (CPR) did not show any statistical significance between cases (35.6%) and controls (39.5%) (Log-rank P-value = 0.959). The COX regression analysis of covariates showed there is no significant relationship between cystectomy and fertility outcome. It showed statistical significance effect of age (hazard ratio [HR] = 0.772), years of infertility (HR = 0.224), and previous endometrioma surgery (HR = 0.180), on fertility chance.ConclusionIn advanced endometriosis with DIE and infertility, fine excision and stripping of the endometrioma along with radical resection of DIE improves fecundity without any significant adverse effect in comparison with patients with intact ovaries.
Journal: European Journal of Obstetrics & Gynecology and Reproductive Biology - Volume 201, June 2016, Pages 46-50