کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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6174705 | 1599831 | 2012 | 5 صفحه PDF | دانلود رایگان |
ObjectiveThe aim of this study was to compare the diagnostic effectiveness of transvaginal sonography (TVS), saline infusion sonohysterography (SIS), and diagnostic hysteroscopy (HS), with the pathologic specimen as a gold standard diagnostic method, in detecting endometrial pathology in premenopausal women with abnormal uterine bleeding.Study designThis prospective cohort study was conducted at Zeynep Kamil Education and Training Hospital, Istanbul, Turkey, and included 89 premenopausal women. All participants were examined first by TVS, further investigated with SIS and HS, and finally dilatation and curettage was performed when needed. The results obtained from these three methods were compared with the pathologic diagnoses. The positive and negative likelihood ratios (LR+ and LRâ) of TVS, SIS and HS were calculated by comparison with the final pathological diagnosis. In addition, area under the curve (AUC) values were also calculated.ResultsPolypoid lesion was the most common abnormal pathology. LR+ and LRâ of TVS, SIS, and HS were 3.13 and 0.15, 9.83 and 0.07, 13.7 and 0.02 respectively in detection of any abnormal pathology, and the AUCs of TVS, SIS, and HS were 0.804, 0.920, and 0.954 respectively. When the three procedures were compared with each other separately, HS had the best diagnostic accuracy, and the diagnostic accuracy of HS and SIS was superior to TVS (p1Â =Â 0.000, p2Â =Â 0.000). For the detection of polypoid lesions, HS was the most accurate diagnostic procedure (AUCÂ =Â 0.947), followed by SIS (AUCÂ =Â 0.894) and TVS (AUCÂ =Â 0.778).ConclusionHS provides the most accurate diagnosis and allows treatment in the same session in premenopausal women with abnormal uterine bleeding.
Journal: European Journal of Obstetrics & Gynecology and Reproductive Biology - Volume 161, Issue 1, March 2012, Pages 66-70