کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6178405 1253255 2016 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Effects of female and male body mass indices on the treatment outcomes and neonatal birth weights associated with in vitro fertilization/intracytoplasmic sperm injection treatment in China
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی زنان، زایمان و بهداشت زنان
پیش نمایش صفحه اول مقاله
Effects of female and male body mass indices on the treatment outcomes and neonatal birth weights associated with in vitro fertilization/intracytoplasmic sperm injection treatment in China
چکیده انگلیسی

ObjectiveTo investigate the combined effects of Chinese couples' body mass indices (BMIs) on the outcomes of IVF or intracytoplasmic sperm injection (ICSI) and the clinical characteristics of their neonates.DesignRetrospective cohort study.SettingUniversity-affiliated reproductive medicine center.Patient(s)A total of 12,061 first fresh IVF/ICSI cycles with autologous oocytes from September 1, 2009 to December 31, 2014.Intervention(s)None.Main Outcome Measure(s)The primary treatment outcome was live birth, and the primary outcome for the neonates was neonatal birth weight (NBW).Result(s)After adjusting for confounders, our study showed that in IVF cycles, couples with a female BMI ≥25 kg/m2 had a significantly higher odds of abortion and a significantly lower odds of live birth than couples with both male and female BMIs <25 kg/m2. Regarding ICSI cycles, no significant relationship was found between the couples' BMIs and the live birth rate. The NBWs of singletons conceived via IVF/ICSI cycles was significantly higher when their parents' BMIs were greater; however, no significant differences were observed in the NBWs of twins conceived via IVF/ICSI cycles.Conclusion(s)Increased female BMI negatively affected live births conceived via IVF. Regarding ICSI, no significant differences were found in the outcomes in terms of parental BMI. The singleton neonates' NBWs increased with parental BMI conceived via IVF/ICSI. However, parental BMI did not significantly affect the NBWs of twins conceived via IVF/ICSI.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Fertility and Sterility - Volume 106, Issue 2, August 2016, Pages 460-466
نویسندگان
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