کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6181484 1253510 2014 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Semen quality of consecutive ejaculates from cancer patients for fertility preservation
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی زنان، زایمان و بهداشت زنان
پیش نمایش صفحه اول مقاله
Semen quality of consecutive ejaculates from cancer patients for fertility preservation
چکیده انگلیسی

ObjectiveTo study variations in semen parameters among cancer patients who visited a sperm banking clinic before undergoing cancer treatment.DesignRetrospective, consecutive study.SettingUniversity-based hospital.Patient(s)Eighty-six patients, diagnosed with various cancers, undergoing multiple semen collections on 5 consecutive days, for fertility preservation, between 2004 and 2013.Intervention(s)None.Main Outcome MeasuresWithin- and between-subject coefficients of variation were estimated using a random-effects analysis of variance to assess the consistency of semen parameters (volume, sperm concentration, motility, rapid motility, total motile sperm count, and computer-based sperm parameters), whereas intraclass correlation coefficients (ICCs) were calculated to assess the size of the between-component of variance relative to the total component of variance.Result(s)When analyzing semen parameters over a maximum of 5 consecutive days, only the semen volume was significantly reduced in day-1 and -3 samples compared with the first sample. Almost all of the parameters showed high ICC values, suggesting that within-subject fluctuations were small relative to the between-subject variability. The highest ICC values were noted in volume (ICC 0.76; 95% confidence interval [CI] 0.52-0.89), followed by total motile count (ICC 0.71; 95% CI 0.30-0.89); the least consistent measure was wobble (ICC 0.14; 95% CI −0.13, 0.51).Conclusion(s)Repeated ejaculates from cancer patients did not show substantial variation in semen quality.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Fertility and Sterility - Volume 102, Issue 4, October 2014, Pages 1124-1129.e3
نویسندگان
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