کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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6181484 | 1253510 | 2014 | 9 صفحه PDF | دانلود رایگان |

ObjectiveTo study variations in semen parameters among cancer patients who visited a sperm banking clinic before undergoing cancer treatment.DesignRetrospective, consecutive study.SettingUniversity-based hospital.Patient(s)Eighty-six patients, diagnosed with various cancers, undergoing multiple semen collections on 5 consecutive days, for fertility preservation, between 2004 and 2013.Intervention(s)None.Main Outcome MeasuresWithin- and between-subject coefficients of variation were estimated using a random-effects analysis of variance to assess the consistency of semen parameters (volume, sperm concentration, motility, rapid motility, total motile sperm count, and computer-based sperm parameters), whereas intraclass correlation coefficients (ICCs) were calculated to assess the size of the between-component of variance relative to the total component of variance.Result(s)When analyzing semen parameters over a maximum of 5 consecutive days, only the semen volume was significantly reduced in day-1 and -3 samples compared with the first sample. Almost all of the parameters showed high ICC values, suggesting that within-subject fluctuations were small relative to the between-subject variability. The highest ICC values were noted in volume (ICC 0.76; 95% confidence interval [CI] 0.52-0.89), followed by total motile count (ICC 0.71; 95% CI 0.30-0.89); the least consistent measure was wobble (ICC 0.14; 95% CI â0.13, 0.51).Conclusion(s)Repeated ejaculates from cancer patients did not show substantial variation in semen quality.
Journal: Fertility and Sterility - Volume 102, Issue 4, October 2014, Pages 1124-1129.e3