Healthy live birth using theophylline in a case of retrograde ejaculation and absolute asthenozoospermia

ObjectiveTo analyze whether the use of ready-to-use theophylline is a feasible option in a case of retrograde ejaculation and absolute asthenozoospermia.DesignCase report.SettingIn vitro fertilization unit of a public hospital.Patient(s)Thirty-one-year-old nulliparous woman, and 39-year-old male with retrograde ejaculation and absolute asthenozoospermia.Intervention(s)Retrieval of postejaculatory urine, restoration of motility using a methylxanthine, intracytoplasmic sperm injection, single-embryo transfer.Main Outcome Measure(s)Sperm motility, fertilization, embryo quality, live birth.Result(s)Successful fertilization and a single-embryo transfer resulted in a healthy live birth.Conclusion(s)Theophylline turned out to be a safe, efficient agent for stimulating immotile spermatozoa in patients with retrograde ejaculation.