Exenteration in the treatment of Stage III/IV vulvar cancer

► Exenteration for advanced vulvar cancer has 5-year survival rates of 62%. Negative lymph nodes are the most important prognostic factor. ► In cases of relapse, exenterative surgery can improve local control and prognosis, with long-term survival of over 100 months being possible in this situation. ► When complete resection is not possible, surgery should only be attempted for palliation.