Synuclein-γ (SNCG) protein expression is associated with poor outcome in endometrial adenocarcinoma

► Overexpression of synuclein-γ is a predictor for aggressive tumor behavior and adverse outcome in patients with endometrial cancer. ► Overexpression of synuclein-γ might play a role in the drug resistance to chemotherapy in patients with endometrial cancer. ► Synuclein-γ merits a future exploration in endometrial cancer research.