کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6183224 1254095 2015 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Intensive postoperative glucose control reduces the surgical site infection rates in gynecologic oncology patients
ترجمه فارسی عنوان
کنترل شدید گلوکز پس از عمل باعث کاهش میزان عفونت محل جراحی در بیماران مبتلا به انکولوژی زنان می شود
کلمات کلیدی
عفونت محل جراحی، جراحی انکولوژی زنان و زایمان، دیابت کنترل گلیسمی شدید، عوارض بعد از عمل، نتیجه جراحی،
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی زنان، زایمان و بهداشت زنان
چکیده انگلیسی


- Patients with DM in gynecologic oncology can have an SSI rate up to 45%.
- We adopted a quality improvement protocol to start postoperative insulin infusion for target blood glucose < 139 mg/dL.
- SSI was lowered by 35%.

ObjectiveSSI rates after gynecologic oncology surgery vary from 5% to 35%, but are up to 45% in patients with diabetes mellitus (DM). Strict postoperative glucose control by insulin infusion has been shown to lower morbidity, but not specifically SSI rates. Our project studied continuous postoperative insulin infusion for 24 h for gynecologic oncology patients with DM and hyperglycemia with a target blood glucose of < 139 mL/dL and a primary outcome of the protocol's impact on SSI rates.MethodsWe compared SSI rates retrospectively among three groups. Group 1 was composed of patients with DM whose blood glucose was controlled with intermittent subcutaneous insulin injections. Group 2 was composed of patients with DM and postoperative hyperglycemia whose blood glucose was controlled by insulin infusion. Group 3 was composed of patients with neither DM nor hyperglycemia. We controlled for all relevant factors associated with SSI.ResultsWe studied a total of 372 patients. Patients in Group 2 had an SSI rate of 26/135 (19%), similar to patients in Group 3 whose rate was 19/89 (21%). Both were significantly lower than the SSI rate (43/148, 29%) of patients in Group 1. This reduction of 35% is significant (p = 0.02). Multivariate analysis showed an odd ratio = 0.5 (0.28-0.91) in reducing SSI rates after instituting this protocol.ConclusionsInitiating intensive glycemic control for 24 h after gynecologic oncology surgery in patients with DM and postoperative hyperglycemia lowers the SSI rate by 35% (OR = 0.5) compared to patients receiving intermittent sliding scale insulin and to a rate equivalent to non-diabetics.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Gynecologic Oncology - Volume 136, Issue 1, January 2015, Pages 71-76
نویسندگان
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