کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6184843 1254345 2015 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Incidental power morcellation of malignancy: A retrospective cohort study
ترجمه فارسی عنوان
سرریز احتمالی قدرت بدخیمی: مطالعه کوهورت گذشته نگر
کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی زنان، زایمان و بهداشت زنان
چکیده انگلیسی


- 0.73% overall incidental malignancy rate among community based sample.
- Higher median uterine weight associated with incidental malignancies.

ObjectiveUterine fibroids often require hysterectomy via a laparotomy or utilizing minimally invasive surgical (MIS) approach. Morcellation is a fragmentation of the uterus into smaller pieces. The objective of this study is to determine the incidence of malignancies found in morcellated specimens at our institution.MethodsWomen who had a minimally invasive hysterectomy, for presumptive benign uterine conditions were identified, included and reviewed. Patients were divided into two groups being either benign disease or malignancies. The continuous variables uterine weight and patient age were tested for normalcy with the Shapiro-Wilk test. The exposure of subspecialist vs general gynecology was interrogated via a Chi-Squared analysis.Results10 cases of malignancies were identified including endometrioid endometrial carcinomas (3), uterine serous carcinoma (1), endometrial stromal sarcomas (ESS) (3), and leiomyosarcomas (LMS) (3). An overall risk of occult cancer on a morcellated specimen was .73%; leiomyosarcoma was 0.22%, endometrial stromal sarcoma 0.22%, and endometrial cancer 0.29%. The median uterine weight for the 10 morcellated malignancies was 293.5 g whereas the median weight for the benign uteri was only 117.5 g giving a theta of − 106 (95% CI − 261,20). There was no difference in patient age or surgeon type between the groups (See Table 1).ConclusionsMorcellation was associated with substantially higher risk of abdominopelvic recurrence and lower disease-free survival. Morcellated uterine malignancies were significantly heavier than benign uteri. Further research on uterine morcellation should focus on decision and cost-benefit analyses to determine the ideal candidate in whom uterine morcellation during minimally invasive hysterectomy would facilitate more good than harm.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Gynecologic Oncology - Volume 136, Issue 2, February 2015, Pages 274-277
نویسندگان
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