کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6189181 | 1256720 | 2013 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Flexible ovarian stimulation in a poor responder: a case report and literature review
ترجمه فارسی عنوان
تحریک انعطاف پذیر تخمدان در پاسخگو ضعیف: گزارش مورد و بررسی ادبیات
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کلمات کلیدی
فاز فولیکولی، امواج فولیکولی، فاز لوتئال، بازیابی اووسیت، تحریک تخمدان، پاسخگو ضعیف
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
زنان، زایمان و بهداشت زنان
چکیده انگلیسی
This article reports on a novel strategy of continuous ovarian stimulation on a poor responder during the follicular and luteal phases of the same menstrual cycle with two oocyte retrievals. It also reviews studies of flexible ovarian stimulation. In our case, a patient, aged 41, who was diagnosed as infertile with very poor ovarian function, sought therapy for IVF. Antral follicles and basic hormones were evaluated on day 2 of the menstrual cycle. The stimulation cycle was commenced with use of 150Â IU/day urinary FSH from day 3, combined with clomiphene citrate and ibuprofen in the late follicular and luteal phases to prevent ovulation. Oocyte retrieval was attempted twice. We performed luteal-phase ovarian stimulation continuously 2Â days after the first failed oocyte retrieval during the follicular phase. Finally, one mature oocyte resulting in a cleavage embryo (8-cell, grade 2) was obtained after the luteal phase stimulation and retrieval, redeeming the previous unsuccessful oocyte retrieval. The case demonstrates that it is practical to obtain mature oocytes and good embryos from maintaining luteal-phase stimulation. For poor ovarian response, continuous stimulation during the follicular and luteal phases can be a solution. The literature review summarizes the clinical outcomes and parameters of flexible ovarian stimulation previously reported, including luteal-phase oocyte retrieval plus in-vitro maturation, ovarian stimulation initiated during the follicular or luteal phase and random-start stimulation. With knowledge gleaned from the case and review of studies, ovarian stimulation may be performed flexibly in special circumstances.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Reproductive BioMedicine Online - Volume 26, Issue 4, April 2013, Pages 378-383
Journal: Reproductive BioMedicine Online - Volume 26, Issue 4, April 2013, Pages 378-383
نویسندگان
Bin Xu, Yanping Li,