کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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6195776 | 1602131 | 2014 | 6 صفحه PDF | دانلود رایگان |
PurposeTo evaluate the lenticular changes associated with congenital iridolenticular choroidal coloboma.DesignRetrospective, observational case series.Methodssetting: Tertiary eye care center in south India. study population: Total of 145 eyes of 98 patients. observation procedure: Medical records of all patients with the diagnosis of congenital iridolenticular choroidal coloboma between January 2011 and December 2012 were reviewed retrospectively for demographic profile, extent of coloboma, and associated lenticular changes.ResultsMedian age of patients at the time of initial visit was 23 years (interquartile range, 13-38 years). The male-to-female ratio was â¼ 1:1. Forty-eight percent had bilateral involvement. Lens showed cataract changes in 68 eyes (48.9%). The most common type of cataract was nuclear sclerosis, which was noted in 51% of cases. A distinct type of cataract, called “coloboma cataract” (characterized by linear opacity in the region of the coloboma), was observed in 29% of cases. Other associated findings were phacodonesis in 3 eyes, dislocation in 3 eyes, and subluxation in 5 eyes. Disc and/or macular involvement in 57 eyes (39.3%) did not influence the type or density of cataract (P > .05).ConclusionsCongenital iridolenticular choroidal coloboma is associated with early cataractous changes. The most common type of cataract is nuclear sclerosis. The type and density of cataract do not seem to be related to the extent of the choroidal coloboma. We suggest a distinct description with the nomenclature “coloboma cataract” to be considered in the clinical grading of cataracts in patients with this condition.
Journal: American Journal of Ophthalmology - Volume 158, Issue 4, October 2014, Pages 827-830.e2