Balance differences in people with Parkinson disease with and without freezing of gait

- Individuals with freezing of gait (FOG) have worse balance than those without FOG.
- Those with FOG have worse reactive postural responses and stability in gait.
- The Mini-BESTest, a time-efficient assessment of balance, is recommended in PD.

BackgroundFreezing of gait (FOG) is a relatively common and remarkably disabling impairment associated with Parkinson disease (PD). Laboratory-based measures indicate that individuals with FOG (PD + FOG) have greater balance deficits than those without FOG (PD − FOG). Whether such differences also can be detected using clinical balance tests has not been investigated. We sought to determine if balance and specific aspects of balance, measured using Balance Evaluation Systems Test (BESTest), differs between PD + FOG and PD − FOG. Furthermore, we aimed to determine if time-efficient clinical balance measures (i.e. Mini-BESTest, Berg Balance Scale (BBS)) could detect balance differences between PD + FOG and PD − FOG.MethodsBalance of 78 individuals with PD, grouped as either PD + FOG (n = 32) or PD − FOG (n = 46), was measured using the BESTest, Mini-BESTest, and BBS. Between-groups comparisons were conducted for these measures and for the six sections of the BESTest using analysis of covariance. A PD composite score was used as a covariate.ResultsControlling for motor sign severity, PD duration, and age, PD + FOG had worse balance than PD − FOG when measured using the BESTest (p = 0.008, F = 7.35) and Mini-BESTest (p = 0.002, F = 10.37), but not the BBS (p = 0.27, F = 1.26). BESTest section differences were noted between PD + FOG and PD − FOG for reactive postural responses (p < 0.001, F = 14.42) and stability in gait (p = 0.003, F = 9.18).ConclusionsThe BESTest and Mini-BESTest, which specifically assessed reactive postural responses and stability in gait, were more likely than the BBS to detect differences in balance between PD + FOG and PD − FOG. Because it is more time efficient to administer, the Mini-BESTest may be the preferred tool for assessing balance deficits associated with FOG.