کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6206536 1265647 2014 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Disease severity affects obstacle crossing in people with Parkinson's disease
ترجمه فارسی عنوان
شدت بیماری بر روی عبور مانع در افراد مبتلا به بیماری پارکینسون تأثیر می گذارد
کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی ارتوپدی، پزشکی ورزشی و توانبخشی
چکیده انگلیسی


- We evaluated the effects of disease severity on obstacle avoidance in people with PD.
- Obstacle avoidance was not affected in the early stages of PD.
- Bradykinesia and hypometria affected obstacle crossing in patients with moderate PD.

The current study evaluated the effects of disease severity on the control of obstacle crossing in people with idiopathic Parkinson's disease (PD). Forty-five subjects participated in the study, including 15 patients with mild PD (classified as stage 1 to 1.5 of the Hoehn and Yahr Rating Scale), 15 patients with moderate PD (classified as stage 2 to 3 of the Hoehn and Yahr Rating Scale), and 15 neurologically healthy individuals. Groups were matched by sex, age, body mass, and body height. The obstacle crossing task required participants to walk along a pathway and step over an obstacle (half of the knee height, positioned in the middle of the pathway). Patients were tested in a typically medicated state. Kinematic data were recorded using an optoelectronic tridimensional system. The outcome measures included spatiotemporal measures of obstacle avoidance. There were no significant differences between patients with mild PD and healthy individuals. Patients with moderate PD exhibited shorter distances for leading toe clearance and leading foot placement after the obstacle than did healthy individuals. Patients with moderate PD tended to exhibit a lower leading horizontal mean velocity during obstacle crossing than did healthy individuals. We found significant negative relationships between obstacle crossing measures and disease severity (score on the motor section of the Unified Parkinson's Disease Rating Scale). These findings suggest that disease severity affects locomotor behavior during obstacle crossing in PD. Specifically, obstacle avoidance was not affected in the early stages of PD; however, bradykinesia and hypometria influenced obstacle crossing in patients with moderate PD.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Gait & Posture - Volume 40, Issue 1, May 2014, Pages 266-269
نویسندگان
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