کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6206621 1265650 2013 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Explaining the variability improvements in gait quality as a result of single event multi-level surgery in cerebral palsy
ترجمه فارسی عنوان
توضیح ارتقاء تنوع در کیفیت راه رفتن به عنوان یک نتیجه از یک عمل جراحی چند سطحی در فلج مغزی
کلمات کلیدی
فلج مغزی، جراحی چند مرحله ای تنها رویداد، تصحیح ظاهر، نتیجه
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی ارتوپدی، پزشکی ورزشی و توانبخشی
چکیده انگلیسی

PurposeThis is a study of all children with spastic diplegic cerebral palsy (Gross Motor Classification System levels II and III) who had single event multi-level surgery (SEMLS) at a single tertiary referral hospital between 1995 and 2008 to identify factors predicting improvement in gait quality as quantified by the gait profile score (GPS). 9 factors (5 dichotomous and 4 continuous, including preoperative GPS) that might be expected to predict outcomes were identified and univariate and multivariable analysis used to explore how these affected outcomes.ScopeData from 121 children were included. The mean improvement in GPS of 4.3° was 2.7 times the minimal clinically important difference. Univariate analysis suggested that preoperative GPS is a very strong predictor of improvement in GPS (p < 10−5) and when this is considered as a covariate only GMFCS level (p = 10−5) and having had previous surgery (p = 0.026) were found to be statistically significant predictors of GPS improvement (p < 0.05). Children of GMFCS level II improved on average by 2° more than those of level III once differences in preoperative GPS had been accounted for.ConclusionChildren with the most abnormal gait patterns preoperatively, and hence those with the most potential to improve are those that improve the most and surgery has clearly been beneficial. Over a quarter of children show changes in GPS which were less than the MCID. The majority of these were those with the least abnormal gait patterns preoperatively and further research is required to establish whether and how such children benefit from SEMLS.

► This is the first large study in which the primary outcome of SEMLS has been reported using the Gait Profile Score (GPS). ► The mean decrease in GPS was 4.3°, 2.7 times the MCID and similar to the change reported in a recent pilot RCT of SEMLS. ► The strongest predictor of improvement in the Gait Profile Score was the baseline Gait Profile Score. ► The mean Gait Profile Score in children at GMFCS level II improved on average by 2° more than those at GMFCS Level III.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Gait & Posture - Volume 38, Issue 3, July 2013, Pages 455-460
نویسندگان
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