کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6213729 1606003 2014 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
A systematic review and meta-analysis of cohort studies of echocardiographic findings in OSA children after adenotonsilectomy
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی بیماری های گوش و جراحی پلاستیک صورت
پیش نمایش صفحه اول مقاله
A systematic review and meta-analysis of cohort studies of echocardiographic findings in OSA children after adenotonsilectomy
چکیده انگلیسی

ContextThere is evidence that OSA in children can be associated with acute and chronic effects on the cardiovascular system due to repetitive episodes of apnea and hypoxemia.ObjectiveTo assess whether there is an association between OSA and echocardiographic findings in children and whether that association persists after adenotonsillectomy.Data sourcesA literature search was conducted based on PUBMED, EMBASE and LILACS.Study selectionChildren with OSA and children who did not have OSA, who were aged ≤12 years.Data extractionTwo reviewers extracted data independently; the risk of bias was assessed by examining the selected sample, the recruitment method, completeness of follow up, and blinding.ResultsSeven studies met all the inclusion criteria and methodological requirements. There was a significant difference with elevated mean pulmonary arterial pressure levels in OSA participants compared to those without OSA at preoperative assessment [mean difference (MD) 8.67; confidential interval (CI) 95% 6.09, 11.25]. OSA participants showed a statistically significant increased interventricular septum (IVS) thickness (mm) [MD 0.60; CI 95% 0.09, 1.11]; and right ventricular (RV) dimension (cm/m) [MD 0.19; CI 95% 0.10, 0.28]. There was also a significant increase in right ventricular (RV) dimension (cm/m) [MD 0.10; CI 95% 0.05, 0.14] in OSA children.ConclusionThere is moderate quality evidence regarding possible association between OSA and right heart repercussions. More prognosis studies are needed, to allow the combination of results in a meta-analysis.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: International Journal of Pediatric Otorhinolaryngology - Volume 78, Issue 10, October 2014, Pages 1571-1578
نویسندگان
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