کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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6221013 | 1607439 | 2015 | 8 صفحه PDF | دانلود رایگان |
ObjectiveTo investigate whether children with a history of infantile colic showed impaired motor development at age 7Â years compared with unaffected peers.Study designWe studied 27â940 children from the Danish National Birth Cohort (1997-2002), including 1879 (6.8%) with a history of infantile colic. Infantile colic was defined according to the modified Wessel criteria as crying for more than 3Â hours per day and more than 3Â days per week. We compared the parental Developmental Coordination Disorder Questionnaire 2007 (DCDQ'07) scores in children with and without infantile colic after adjustment for intrauterine exposures, feeding type, parity, maternal age, socioeconomic status, Apgar score, gestational age, and birth weight.ResultsChildren with a history of infantile colic had an elevated risk of scoring above the predefined cutoff limit of possible or suspected developmental coordination disorder (OR, 1.3; 95% CI, 1.0-1.7; P = .034). The mean total DCDQ'07 score was â0.4 point (95% CI, â0.8 to 0) lower in children with a history of infantile colic. Moreover, they were at higher risk for a low total score (OR for a 10-point decrease, 1.1; 95% CI, 1.0-1.1; PÂ =Â .006) and a low general coordination score (OR, 1.3; 95% CI, 1.1-1.5, P = .000) in the DCDQ'07. All associations appeared to be stronger among boys, but no statistically significant effect measure modification between infantile colic and sex was found.ConclusionWe found no evidence of a strong association between infantile colic and developmental coordination disorder in this large Danish cohort.
Journal: The Journal of Pediatrics - Volume 167, Issue 3, September 2015, Pages 725-730.e2