کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6222536 | 1607457 | 2014 | 5 صفحه PDF | دانلود رایگان |
ObjectiveTo determine the frequency of medical problems in a large population of children with Down syndrome.Study designStudy population included 440 children with Down syndrome (ages 3-14Â years) identified primarily through the New York Congenital Malformations Registry. Parents completed questionnaires on medical problems.ResultsOur study population was predominately White (92.3%), non-Hispanic (72.3%) with at least 1 college educated parent (72.3%). The prevalence of medical problems was as follows: heart disease (55%), hearing problem (39%), vision problem (39%), thyroid disease (27%), celiac disease (5%), alopecia (5%), seizures (7%), asthma/reactive airway disease (32%), diabetes (1%), and juvenile rheumatoid arthritis (0.2%). Of the children with heart disease, 58% needed surgery at a mean age of 9Â months. Of the children with hearing loss, 29% were identified on newborn screening and 13% used an amplification device. Of the children with thyroid disease, 31% were diagnosed in the newborn period. Only 7% of these children with Down syndrome had no medical problem listed.ConclusionPrevalence data of medical illnesses in a large population of children with Down syndrome provide us with data to support implementation of the American Academy of Pediatrics guidelines for health supervision for children with Down syndrome. The long-term health implications of the conditions we surveyed will be important for decreasing morbidity and increasing overall health and wellness into adulthood.
Journal: The Journal of Pediatrics - Volume 164, Issue 4, April 2014, Pages 871-875