کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6224508 1607482 2012 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Total Serum Bilirubin Exceeding Exchange Transfusion Thresholds in the Setting of Universal Screening
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی پریناتولوژی (پزشکی مادر و جنین)، طب اطفال و بهداشت کودک
پیش نمایش صفحه اول مقاله
Total Serum Bilirubin Exceeding Exchange Transfusion Thresholds in the Setting of Universal Screening
چکیده انگلیسی

ObjectiveTo describe the incidence and predictors of total serum bilirubin (TSB) levels that meet or exceed American Academy of Pediatrics (AAP) exchange transfusion (ET) thresholds in the setting of universal screening.Study designWe conducted a retrospective cohort analysis of electronic data on 18 089 newborns ≥35 weeks gestation born at Northern California Kaiser Permanente Medical Care Program hospitals implementing universal TSB screening in 2005 to 2007, with chart review for subjects with TSB levels reaching the AAP threshold for ET.ResultsThe outcome developed in 22 infants (0.12%); 14 (63.6%) were <38 weeks gestation. Only one infant received an ET; none of the infants had documented sequelae. The first TSB was at least high-intermediate risk on the AAP risk-nomogram for all 22 infants and high-risk for those ≥38 weeks, but was less than the phototherapy level in 15 infants (68%). Of these 15 infants, 2 failed phototherapy and 13 did not have a TSB repeated in <24 hours. However, re-testing all infants at high-intermediate risk or greater would have required 2166 additional bilirubin tests.ConclusionScreening was sensitive but not specific for predicting exchange threshold.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: The Journal of Pediatrics - Volume 160, Issue 5, May 2012, Pages 796-800.e1
نویسندگان
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